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The Paper Rejection Repository

Nobody likes to receive a letter from the editor of your favorite journal letting you know that your paper was rejected. Some journals have begun including reviewers’ comments with accepted papers to make the views of experts available to the reader. However, often the paper has been submitted to several journals and rejected before it is finally accepted. The rejection letters and comments are equally useful in helping to judge what kind of papers might be acceptable to a journal, and what kind of comments lead to rejections. Rather than hiding these low points in the trajectory of a scientific paper, this forum offers a place to publish these letters and comments to educate others.

If you would like to post your own rejection letters and comments, please log in (register on the page first), click on ‘Upload rejection’, fill in details requested on the form and attach a PDF containing all the material you would like to share. If you cannot answer the questions posed by the captcha on the registration page, please email Nikolaus Grigorieff for help.

Please remove any information that might be regarded as confidential and post only rejections of papers that were ultimately accepted by a journal.

For some background on this repository, please read our blog post on The repository was also highlighted in posts on Science Careers and The Scientist.


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Posted On Title Rejected Bysort icon Ultimately Published In
1 Jul 2016 Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril Nature Comm, Nature Chem, eLife 2016, PNAS 113:6200–6205 @
28 Jul 2010 Ito Channels Are Octomeric Complexes with Four Subunits of Each Kv4.2 and K+ Channel-interacting Protein 2 Nature Neuroscience 2004, J. Biol. Chem. 279:5549–5554 @
28 Jul 2010 Three-Dimensional Structure of a Voltage-Gated Potassium Channel at 2.5 nm Resolution Nature, NSMB 2001, Structure 9:215–220 @
13 Dec 2013 Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State Nature, NSMB 2013, PNAS 110:20994–20999 @
23 Jul 2010 Quaternary Structure of a Mature Amyloid Fibril from Alzheimer's Aβ(1-40) Peptide Nature, PNAS 2006, J. Mol. Biol. 362:347–354 @
28 Jul 2010 Paired β-sheet structure of an Aβ(1-40) amyloid fibril revealed by electron microscopy Nature, Science 2008, PNAS 105:7462–7466 @
2 Mar 2012 Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface NSMB, Mol. Cell 2012, PNAS 109:3353–3358 @
31 Aug 2012 Movies of ice-embedded particles enhance resolution in electron cryo-microscopy PNAS, Nature Methods 2012, Structure 20:1823–1828 @
28 Jul 2010 Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM Science 2009, PNAS 106:10644–10648 @
14 Dec 2010 Atomic model of an infectious rotavirus particle Science 2011, EMBO J. 30:408-416 @